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Neuroimaging study of dopaminergic neurotransmission in depresive state

Neuroimaging study of dopaminergic neurotransmission in depresive state - Neuroimaging study of dopaminergic neurotransmission in depresive state

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000009404
Enrollment
60
Registered
2012-11-30
Start date
2012-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mood disorder and adjustment disorder

Interventions

PET, MRI PET, MRI PET, MRI

Sponsors

National Institute of Radiological Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion criteria for patients 1) Age, 20-60 years 2) Diagnosis, major depressive disorder and adjustment disorder as defined by the criteria of DSM-IV-TR 3) Subjects who have the ability to provide informed consent Inclusion criteria for normal controls 1) Age, 20-60 years 2) No current or past history of psychiatric disorders and no current medical conditions 3) Subjects who have the ability to provide informed consent 4) Subjects who are judged by researchers as suitable for participation in the study

Exclusion criteria

Exclusion criteria: Exclusion criteria for patients 1) Serious suicidal ideation or behavior 2) Co-morbid other psychiatric disorders including drug dependence 3) Subjects taking antidepressants or antipsychotic agents within 28 days before the examination 4) Existence of brain organic disease, including current or past history of cerebrovascular disease, Parkinson's disease, and other related disorders 5) Existence of serious medical illnesses 6) Subjects who are judged by researchers as not suitable for participation in the study

Design outcomes

Primary

MeasureTime frame
The association of Dopamine D1 and D2 receptor binding potentials with clinical features

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026