CKD patients
Conditions
Interventions
The patients with CKD accompanied by hyperlipidemia (n=50) were administered 10mg of atorvastatin orally once a day. However, the maximum daily dose of atorvastatin is 40mg. The period of this study i
Sponsors
Division of Nephrology, Juntendo University Faculty of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients are eligible if they are compatible with the following criteria. 1. CKD patients accompanied with hyperlipidemia. (administration of statin and /or ethyl icosapentate are not restricted) 2. Patients who agreed with the participation of the study based on informed consent before the study initiation, and filled in signature sealing or a signature and a date.
Exclusion criteria
Exclusion criteria: Patients are excluded if they are compatible with any one of the following criteria. 1. Patients with a history of hypersensitivity for an ingredient of atorvastatin. 2. Patients whose liver function is thought to decrease; acute hepatitis, acute aggravation of the chronic hepatitis, cirrhosis, liver cancer, jaundice 3. A pregnant woman or the woman who may be pregnant and nursing mother. 4. Patients receiving telaprevir. 5. Patients with significant psychic disturbance or drug dependence disease or alcoholism. 6. Patients that going to hospital of all follow-up seems to be impossible. 7. Patients who are not able to understand a test instruction from medical experts of the client side or the doctors involved in the study. 8. Patients who judged as inadequate by the doctors involved in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of urinary albumin | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Lipid metabolism: LDL, HDL, TG, Apolipoprotein fractionation, MDA-LDL 2.High sensitive CRP 3.ADMA 4.Urinary L-FABP 5.Urinary 8-OHdG 6.ABI and CAVI 7.Carotid ultrasonography 8.Examination of the fundus | — |
Countries
Japan
Contacts
Public ContactHitoshi Suzuki
Juntendo University Faculty of Medicine Department of Internal Medicine, Division of Nephrology
Outcome results
None listed