To Sprinkle Vancomycin Powder or Ampicillin into Operative Field Decrease Severe Surgical Site Infection in Thoracolumbar Fusions. Double blind prospective RCT

To Sprinkle Vancomycin Powder or Ampicillin into Operative Field Decrease Severe Surgical Site Infection in Thoracolumbar Fusions. Double blind prospective RCT - Sprinkling Vancomycin or Ampicillin Powder into Operative Field.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009377

Enrollment

200

Registered

2012-11-22

Start date

2012-11-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing thoracolumbar fusion surgery

Interventions

Sprinkling Vancomycin Powder into Operative Field and bone tips after Thoracolumbar fusion surgery. Sprinkling Ampicillin Powder into Operative Field and bone tips after Thoracolumbar fusion surgery.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All Patients undergoing thoracolumbar fusion surgery.

Exclusion criteria

Exclusion criteria: 1. The patients with putting the drainage more than three days after the fusion surgery. 2. The patients with performing antibiotic DIV more than four days after the fusion surgery. 3. The patients with allergy for Vancomycin and Ampicillin.

Design outcomes

Primary

Measure	Time frame
Surgical site infection (SSI) within one year after the surgery based on the international SSI definition.	—

Countries

Japan

Contacts

Public ContactMikinobu Takeuchi

Aichi Medical University Spine Center

neuromicky@hotmail.com0561-62-3311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026