Gastric cancer patients with peritoneal metastases
Conditions
Interventions
Injection of 2-8 MBq/kg 18F-FLT, PET/CT imaging study of one hour, and blood examinations after one week of inspections.
Sponsors
Department of Gastrointestinal Oncology, National Cancer Center Hospital in Japan
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: [A-part] 1.Equal to or over 20 years. 2.Established diagnosis of gastric cancer by histology or cytology. 3.Rough peritoneal metastases are detected by diagnostic imaing performed within 4 weeks. 4.Performance status:0-2. 5.Main organs functions must be normal. 6.Written informed concent can be obtained. [B-part] 1.Equal to or over 20 years. 2.Established diagnosis of gastric cancer by histology or cytology. 3.Peritoneal metastases are detected by diagnostic laparoscopy or surgical finding performed within 4 weeks. 4.Performance status:0-2. 5.Main organs functions must be normal. 6.Written informed concent can be
Exclusion criteria
Exclusion criteria: 1.Peritoneal metastases detected only by cytology of ascites. 2.Patients who have alcoholic hyper- sensitivity. 3.Patients with active infection. 4.Pregnant women or women who have the possibility to be pregnant or lactating woman. 5.Patients who are considered to be ineligible by referring physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity of 18F-FLT PET/CT in the diagnosis of peritoneal metastases of gastric cancer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety of 18F-FLT Sensitivity of 18F-FLT PET/CT in the diagnosis of primary or metastatic lesion of gastric cancer. | — |
Countries
Japan
Contacts
Public ContactYoshitaka Honma
National Cancer Center Hospital in Japan Department of Gastrointestinal Oncology
Outcome results
None listed