Chronic Kidney Disease
Conditions
Interventions
Experimental period: 2 years Number of times: single dose, 30 times (at least 1 week interval) Test article: commercially available foods (30 different foods) containing 200 mg phosphate. A subject
Sponsors
Department of Clinical Nutrition, Institute of Health Biosciences, University of Tokushima Graduate School
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Healthy young men and women (20-39 years old). Subjects should not be: BMI=25 or higher, smoker, under pregnancy and lactation.
Exclusion criteria
Exclusion criteria: Following subject(s) should be excluded: history or under treatment of heart disease, kidney disease, liver disease, gastrointestinal disease, brain disease, diabetes, hypertension and/or dyslipidemia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| post-prandial serum phosphate, post-prandial urinary phosphate excretion, post-prandial intact-PTH, and post-prandial endothelial function (FMD and/or endo-PAT) | — |
Secondary
| Measure | Time frame |
|---|---|
| Post-prandial blood glucose, serum creatinine, blood urea nitrogen, blood pressure, serum Na, K, Cl, Ca, triglyceride, total cholesterol, HDL-cholesterol, LDL-cholesterol, uric acid, insulin, 1,25-dihydroxyvitamin D, FGF23, urinary creatinine excretion, urinary Na excretion, urinary K excretion, urinary Ca excretion. | — |
Countries
Japan
Contacts
Public ContactYutaka Taketani
University of Tokushima Graduate School, Institute of Health Biosciences Department of Clinical Nutrition
Outcome results
None listed