Efficacy and safety of acetaminophen in the treatment of patients with head and neck cancer

Efficacy and safety of acetaminophen in the treatment of patients with head and neck cancer - Acetaminophen in the treatment of patients with head and neck cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009292

Enrollment

Registered

2012-11-08

Start date

2012-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancer

Interventions

Acetaminophen Etodolac

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Japanese patients who 1.were diagnosed as having head and neck cancer. 2.are undergoing chemoratiotherapy. 3.are complaining of pain (NRS1-6) caused by mucositis. 4.have not taken analgesic agents yet. 5.are thought to be relieved by non-opioid analgesics. 6.can take analgesic agents orally. 7.can give written informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with peptic ulcer 2.Patients with severe blood disorder 3.Patients with severe liver dysfunction 4.Patients with severe renal dysfunction 5.Patients with severe cardiac dysfunction 6.Patients with known hypersensitivity to acetaminophen or etodolac 7.Female patients who are pregnant, lactating or possibly pregnant 8.Patients who are judged inappropriate for the clinical trial by attending physician

Design outcomes

Primary

Measure	Time frame
Pain scores while eating	—

Countries

Japan

Contacts

Public ContactKen-ichi Kaneko

Nagasaki University Hospital Department of Otolaryngology

kkaneko@ba2.so-net.ne.jp095-801-7711

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026