Non Squamous Non Small Cell Lung Cancer
Conditions
Sponsors
Kansai Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Histologically or cytologically confirned advanced non-small-cell lung cancer (NSCLC) 2)stage IV or postoperative recurrence patients 3)Patients previously treated with platinum- based chemotherapy for four cycles and except PD cases 4)more than 20 years old 5)ECOG PS 0-2 6)Measurable lesion 7)Adequate organ function 8)patients who can take orally 9)Signed informed consent
Exclusion criteria
Exclusion criteria: 1)Interstitial pneumonia or pulmonary fibrosis on chest X-ray 2) History of serious drug allergy 3)Patients with active double cancer 4)Patients with pleural or pericardial effusion ,or ascites 5)Being treated with flucytosine. 6) History of serious infection 7)History of HBs antigen 8)Patients with significant complications a) Uncontrolled angina pectoris, myocardial infarction, heart failure within 3 months b)Uncontrolled diabetes or hypertension c)Current severe infection, or suspicious of severe infection d) Patients whose participation in the trial is judged to be inappropriate by the attending doctor. (e.g., ileus, bleeding tendency, diarrhea and varicella) 9 )Symptomatic brain metastases 10)Patients with pregnancy or lactation 11)patients whom it is judged to have difficulty in participation in study because of psychosis or neurologic disease 12)Patients whose participation in the trial is judged to be inappropriate by the attending doctor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression Free Survival | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall Survival, Response Rate, Safety | — |
Countries
Japan
Outcome results
None listed