common cold, infectious disease
Conditions
Interventions
Jelly containing lactic acid bacteria, one cup per day, for 12 weeks
Placebo Jelly, one cup per day, for 12 weeks
Sponsors
Fukushimura Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Elderly individuals living in nursing care center, who are scheduled to receive influenza vaccination.
Exclusion criteria
Exclusion criteria: 1) Individuals severely affected with hepatic dysfunction, renal dysfunction, cardiovascular disorder, respiratory dysfunction, endocrine disorder, metabolic disorder, intestinal obstruction, cancer and dyslipidemia. 2) Individuals with allergy to soybean, peach and gelatin, which are contained in the tested foods. 3) Individuals daily consuming supplements of lactic acid bacteria except those provided by meals. 4) Other individuals judged as inappropriate for the study by the physician in charge.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence, number of subjects and duration regarding symptoms of common cold (nose, throat, fever, pain) and infectious disease such as influenza virus infection. | — |
Secondary
| Measure | Time frame |
|---|---|
| NK cell activity, neutrophil phagocytic activity, neutrophil bactericidal activity, antibody titers in response to the vaccine, immunoglobulin, salivary sIgA and composition of intestinal microbiota. | — |
Countries
Japan
Contacts
Public ContactHiroyasu Akatsu
Fukushimura Hospital Choju Medical Institute
Outcome results
None listed