Examination of intraoperative use of tranexamic acid in patients undergoing radical hysterectomy

Examination of intraoperative use of tranexamic acid in patients undergoing radical hysterectomy - Examination of intraoperative use of tranexamic acid in patients undergoing radical hysterectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009226

Enrollment

100

Registered

2012-11-01

Start date

2012-12-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

uterine cancer

Interventions

A loading dose of 500mg of tranexamic acid is infused slowly intravenously 20 minutes before surgery,and a continuous intravenous infusion of tranexamic acid is given at a rate of 250mg/h from surgica

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients older than 18 years old and undergoing radical hysterectomy(associated with lymph node dissection when required for oncological radicality) agreed to participate in this traial.

Exclusion criteria

Exclusion criteria: Exclusion criteria are atrial fibrillation,coronary artery disease treated with drug eluting stent,severe chronic renal failure,congenital or acquired thrombophilia,and known or suspected allergy to tranexamic acid.

Design outcomes

Primary

Measure	Time frame
intraoperative blood loss	—

Secondary

Measure	Time frame
the rate of intraoperative transfusion,perioperative complication rate	—

Countries

Japan

Contacts

Public ContactTakaya Hojo

Tokyo Metropolitan Tama Medical Center Department of Anaesthesia

042-323-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026