lung cancer
Conditions
Interventions
A group which are used desflrane as general anesthetics.
A group which are used propofol as general anesthetics.
Sponsors
Juntendo University, Faculty of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: -Patients agree to participate in the study -Patients undergoing lung cancer surgery requiring OLV. -ASA 1-2
Exclusion criteria
Exclusion criteria: Patients with any of the following will be excluded from lung cancer patients. -NYHA Classification more than II -Respiratory dysfunction VC or FEV1 is less than 50% -Pulmonary hypertension with mean pulmonary arterial pressure more than 30mmHg -Coagulation dysfunction -The administration of steroids and immunosuppressive agents within 3 months prior to surgery -Infection with active inflammation -Pneumonectomy patients -Cases of epidural anesthesia is contraindicated
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Blood samples will be collected Immediately after the induction of anesthesia in bilateral lung ventilation, 30 minutes after the start of OLV, one hour after the start of OLV and at the end of surgery in bilateral lung ventilation. Calculates the P / F ratio from the blood gas value. Evaluation Criteria for Emergence: -The time from the discontinuation of anesthesia to eye opening -The time from the discontinuation of anesthesia to extubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| -To confirm the effect of HPV by measuring changes in pulmonary blood flow. And also investigate the correlation between the attenuation of pulmonary blood flow and blood oxygen concentration. - The time from the discontinuation of anesthesia to able to hold hand - The time from the discontinuation of anesthesia to orientation(state place, state name, state the date of birth) | — |
Countries
Japan
Contacts
Public ContactIzumi Kawagoe
Juntendo University Dept. of Anesthesiology and Pain Medicine
Outcome results
None listed