study for correlation between genetic polymorphism of FP receptor and effect of prostaglandin treatment on preperimetric glaucoma

study for correlation between genetic polymorphism of FP receptor and effect of prostaglandin treatment on preperimetric glaucoma - correlation between genetic polymorphism of FP receptor and effect of prostaglandin treatment on glaucoma

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000009207

Enrollment

Registered

2012-10-29

Start date

2012-10-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1 Over age 20 , under age 80. 2 male or femal. 3 Gonioscopy classification of Shaffer 3 or 4. 4 no corneal abnormalities that may interfere measurement of intraocular pressure by Glodman applanation tonometer 5 no retinal disease that can affectnerve fiber layer thickness. (no history of laser treatment on retina) 6 not secondary glaucoma. 7 phakic or pseudophakic eye 8 spherical equivalent is within +3 to -8D 9 corrected visual acuity>= 20/20 10 intraocular pressure <= 21 mmHg identified twice within six months. 11 more than 1 segment detected as <5% percentile at 6,7,8,10,11 or 12 o'clock segmentation in cpRNFLT analysis by OCT, examed twice within 6 months. 12 glaucomatous visual field abnormality is not observed by Humphery Feile Analyzer(HFA) within six months, also the result is reliable.

Exclusion criteria

Exclusion criteria: case without consent, or Patients assessed as inappropriate to be enrolled in this observational study by the physician

Design outcomes

Primary

Measure	Time frame
single nucleotide polymorphisms (SNP)of FP receptor and endothelin A/B receptor	—

Countries

Japan

Contacts

Public ContactRyu, Morin

Tohoku Univ. Graduate school of medicine ophthalmology

ryu@oph.med.tohoku.ac.jp022-7177294

Outcome results