Comparative study of the effects of different intra-operative end-tidal CO2 levels on intra and post-operative anesthesia complication in adult patients under general anesthesia for PCNL.

Comparative study of the effects of different intra-operative end-tidal CO2 levels on intra and post-operative anesthesia complication in adult patients under general anesthesia for PCNL. - Effects of CO2 levels on anesthesia complication

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009161

Enrollment

Registered

2012-10-24

Start date

2012-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A descriptive study has shown relative safety and benefits of higher CO2 levels and mild hypercapnia. Effects of different levels of end-tidal CO2 concentration have not been evaluated in a controlled trial.

Interventions

Mild hypocapnia Normocapnia Mild hypercapnia

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient consent Adult Surgery PCNL

Exclusion criteria

Exclusion criteria: Addiction Smoker History of cardiorespiratory Elevated BUN or creatinine BMI > 30 History of PONV Recent anesthesia with volatiles

Design outcomes

Primary

Measure	Time frame
Rates of cardio-respiratory complications	—

Secondary

Measure	Time frame
Mean time to full recovery Mean recovery room stay duration Postoperative rates of shiverng, restlessness, nausea and vomiting	—

Countries

Asia(except Japan)

Contacts

Public ContactMahmoud Saghaei

Isfahan University of Medical Sciences Department of Anesthesia

mahmood.saghaei@gmail.com+983116249031

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026