Study of therapeutic effect of esomeprazole on patients with gastroesophageal reflux disease associated with paroxysmal atrial fibrillation

Study of therapeutic effect of esomeprazole on patients with gastroesophageal reflux disease associated with paroxysmal atrial fibrillation - Effect of esomeprazole on paroxysmal atrial fibrillation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009151

Enrollment

Registered

2012-11-01

Start date

2012-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

paroxysmal atrial fibrillation and gastroesophageal reflux disease

Interventions

pharmacological intervention

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients with paroxysmal atrial fibrillation (AF) and gastroesopageal reflux disease (GERD), i.e., AF paroxysms was so frequent as 2 - 3 times per month, and GERD was diagnozed as F-scale scores of 8 points or more.

Exclusion criteria

Exclusion criteria: patients with drug allergy for proton pump inhibitors

Design outcomes

Primary

Measure	Time frame
Improvement of F-scale scores by esomeprazole	—

Secondary

Measure	Time frame
Suppressive effect of esomeprazole on paroxysmal atrial fibrillation evaluated by Holter monitoring	—

Countries

Japan

Contacts

Public ContactToru Maruyama, MD.

Kyushu University Faculty of Arts and Science

maruyama@artsci.kyushu-u.ac.jp+81-92-583-7685

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026