Effects of continuous traditional Japanese massage therapy (Anma therapy) for cancer survivors: a randomized controlled trial

Effects of continuous traditional Japanese massage therapy (Anma therapy) for cancer survivors: a randomized controlled trial - RCT of Anma massage therapy for cancer survivors

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009097

Enrollment

Registered

2012-10-12

Start date

2012-11-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer survivors histologically confirmed to have had uterine cervical, endometrial, ovarian, fallopian tube, or peritoneal cancer in the past but with no recurrence for more than three years since receiving standard medical treatment.

Interventions

Anma massage group receiving a 40-minute Anma massage session weekly over a two-month intervention period (total of eight Anma massage sessions). Control group being followed by medical doctors and n

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Female cancer survivor histologically confirmed to have uterine cervical, endometrial, ovarian, fallopian tube, or peritoneal cancer in the past but with no recurrence in more than three years since receipt of standard medical treatment, who is over 20 years of age at the time of registration to the study, and who is selected by her doctor to be eligible for the study.

Exclusion criteria

Exclusion criteria: Progressive infectious disease, receiving treatment for organ disease (e.g. heart, liver, kidney), cognitive disorder.

Design outcomes

Primary

Measure	Time frame
Primary endpoint is change in the severity of subjective symptoms assessed using a visual analogue scale (VAS). VAS assessments are completed before and after the first intervention session and at the end of a continuous two-month period of intervention sessions.	—

Secondary

Measure	Time frame
Scores for the Japanese versions of the Hospital Anxiety Depression Scale (HADS), European Organization for Research and Treatment of Cancer QLQ-C30 (EORTC QLQ-C30), and the Mental Adjustment to Cancer (MAC Scale). In addition, measurements of oxidative stress in urine (8-hydroxydeoxyguanosine [8-OH-dG] etc.), salivary cortisol, chromogranin A, and secretory immunoglobulin A (s-IgA). Self-reported questionnaire and urine sample testing are conducted before the first intervention session and at the end of the continuous two-month period of intervention sessions. Salivary samples are also collected before and after the first intervention session and at the end of a continuous two-month period of intervention sessions.	—

Measure

Time frame

Scores for the Japanese versions of the Hospital Anxiety Depression Scale (HADS), European Organization for Research and Treatment of Cancer QLQ-C30 (EORTC QLQ-C30), and the Mental Adjustment to Cancer (MAC Scale). In addition, measurements of oxidative stress in urine (8-hydroxydeoxyguanosine [8-OH-dG] etc.), salivary cortisol, chromogranin A, and secretory immunoglobulin A (s-IgA). Self-reported questionnaire and urine sample testing are conducted before the first intervention session and at the end of the continuous two-month period of intervention sessions. Salivary samples are also collected before and after the first intervention session and at the end of a continuous two-month period of intervention sessions.

—

Countries

Japan

Contacts

Public ContactNozomi DONOYAMA

Tsukuba University of Technology Department of Health, Faculty of Health Sciences

donoyama@k.tsukuba-tech.ac.jp029-858-9631

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026