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Deferoxamine for patients with advanced pancreatic cancer: pilot study

Deferoxamine for patients with advanced pancreatic cancer: pilot study - DFO for pancreatic cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000009054
Enrollment
10
Registered
2012-10-09
Start date
2012-10-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatic cancer

Interventions

Administration of Deferoxamine

Sponsors

First Department of Internal Medicine, Yamaguchi University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Advanced pancreatic cancer diagnosed based on the histological findings (StageIVa<=) 2)Standard treatment-resistant patients (GEM and/or TS-1) 3)Patients who have no influence on previous treatment 4) Performance status (PS) 0 or 1 5) Favorable function of major organ (bone marrow, kidny, heart), and meeting criteria as fellows: (1) neutrophil >= 1500/mm3 (2) platelet count>= 50000/mm3 (3) hemogrobin level >= 8.5g/dl (4) serum creatinine level < 2mg/dl 6) age >= 20years, male and female

Exclusion criteria

Exclusion criteria: 1) Severe coexisting illness 2) Active bouble cancers 3) serum creatinine level >= 2mg/dl 4) Past history of hypersensitivity for drugs including iodine and contrast agent 5) Patients with pregnancy, lactation or possibility of pregnancy 6) Patients who judged as inadequacy due to other reasons by the doctor

Design outcomes

Primary

MeasureTime frame
Safety

Secondary

MeasureTime frame
Overall survival, progression-free survival, anti-tumor effect

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026