Effect of combination therapy with amlodipine and atorvastatin on blood pressure varaiability, vascular function and renal function in hypertensive patients with chronic kidney disease

Effect of combination therapy with amlodipine and atorvastatin on blood pressure varaiability, vascular function and renal function in hypertensive patients with chronic kidney disease - Effect of combination therapy with amlodipine and atorvastatin hypertensive patients with chronic kidney disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009045

Enrollment

Registered

2012-10-05

Start date

2012-10-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension with chronic kidney disease (CKD stage 1-4)

Interventions

Amlodipine/atorvastatin combination tablets

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) CKD stage 1-4 2) Under the antihypertensive therapy 3) Office sytolic BP >= 130mmHg Office diastolc BP >= 80mmHg 4) LDL-cholesterol >= 100mg/dl

Exclusion criteria

Exclusion criteria: 1) CKD stage 5 or 5D 2) Patients who have allergy for amlodipine or atorvastatin 3) Patients who are pregnant 4) Patients who are unfit for this study

Design outcomes

Primary

Measure	Time frame
Body weight, abrominal circumference Office blood pressure and its vriability Blood examination, Urine examination Vascular function (ABI/PWV, CAVI, FMD etc...)	—

Secondary

Measure	Time frame
Body weight, abrominal circumference Office blood pressure and its vriability Blood examination, Urine examination Vascular function (ABI/PWV, CAVI, FMD etc...)	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026