Spinal cord tumors, spinal disorders
Conditions
Interventions
The degree of sedation is evaluated on the basis of the value of the bispectral index calculated by BIS monitoring of brain waves, and the dose of dexmedetomidine is adjusted during surgery while moni
Sponsors
Niigata University Medical and Dental Hospital, Anesthesiology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who are scheduled to undergo surgery of the spine or spinal cord at a Niigata university Medical and Dental hospital and need intraoperative spinal cord monitoring, those who are scheduled to be admitted to the ICU after surgery, those with histories of egg and soy bean allergy or convulsive attacks, those in whom the use of ketamine is difficult, those with GABA (A) receptor deletion, and those who consented to participation in the study after a sufficient explanation.
Exclusion criteria
Exclusion criteria: 1. Patients who are or may be pregnant. 2. Patients undergoing blood purification therapy. 3. Patients with cardiovascular disorders. 4. Patients with reduced cardiac function. 5. Patients with a reduced circulating blood volume. 6. Patients with liver dysfunction. 7. Patients with kidney dysfunction. 8. Old patients (75 years or above). 9. Patients judged to be inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the depth of anesthesia by BIS monitoring to validate the hypothesis that dexmedetomidine is effective as a general anesthetic. | — |
Secondary
| Measure | Time frame |
|---|---|
| To measure the amplitude and latency of the waveform obtained by spinal cord monitoring under general anesthesia using dexmedetomidine, and to evaluate its clinical advantages and safety. | — |
Countries
Japan
Contacts
Public ContactHideaki Ishii
Niigata University Medical and Dental Hospital, Anesthesiology
Outcome results
None listed