Effect of Telmisartan on the post stroke cognitive decline: a randomized open label study

Effect of Telmisartan on the post stroke cognitive decline: a randomized open label study - Effect of Telmisartan on the post stroke cognitive decline: a randomized, open label study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009033

Enrollment

100

Registered

2012-10-05

Start date

2012-10-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral infarction

Interventions

Telmisartan group: Taking telmisartan Non-Telmisartan group: Taking antihypertensive drug other than renin-angiotensin system supressor)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with a recent ischemic stroke (14 days >=). 2) Hypertensive patients (SBP =>140 mmHg and or DBP =>90 mmHg).

Exclusion criteria

Exclusion criteria: 1) Age <65 years 2) modified Rankin Scale >4 3) NIHSS Best Language (Aphasia) score >1 4) NHISS Dysarthria score >1 5) Patients with pre-existing dementia 6) Patients who are not possible to communicate by mental disorder or disturbance of consciousness

Design outcomes

Primary

Measure	Time frame
The rate of change in the MoCA-J score and the MMSE score at 3, 12, 24 months after baseline.	—

Secondary

Measure	Time frame
Stroke recurrence	—

Countries

Japan

Contacts

Public ContactKazuo Yamashiro

Juntendo University Department of Neurology

Kazuo-y@juntendo.ac.jp03-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026