Evaluate the Interaction Between Antiplatelet Effect of Clopidogrel and Proton Pump Inhibitor

Evaluate the Interaction Between Antiplatelet Effect of Clopidogrel and Proton Pump Inhibitor - Interaction of Clopidogrel and PPI

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009019

Enrollment

Registered

2012-10-01

Start date

2012-10-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ischemic heart disease, gastric ulcer, Gastroesophageal Reflux Disease

Interventions

Taking omeprazole Taking eomeprazole

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients taking DAPT (aspirin and clopidogrel) due to ischemic heart disease, and taking Proton pump inhibitor due to peptic ulcer or gastroesophageal Reflux Disease

Exclusion criteria

Exclusion criteria: Contraindication of aspirin and clopidogrel Patients taking Warfarin Patients performed thrombolysis within 2 weeks Patients taking other antiplatelet agents

Design outcomes

Primary

Measure	Time frame
Antiplatelet effect of clopidogrel evaluated by VerifyNow	—

Countries

Japan

Contacts

Public ContactJunichi Tazaki

Graduate School of Medicine, Kyoto University Department of Cardiovascular Medicine

jun1@kuhp.kyoto-u.ac.jp075-751-4254

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026