maxillary carcinoma
Conditions
Interventions
Transarterial infusion of cisplatinum to feeding artery of maxillary carcinoma and irradiation to the same lesion.
Sponsors
National Cancer Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Maxillaruy carcinoma which was pathologically diagnosed as squamous cell carcinoma. Tumor stage is T3 or T4 based on UICC 7th edition. Selective angiography of feeding artery is feasible. Life expectancy is 8 weeks or more. Performance status (ECOG) is 1, 2 or 3. Function of major organs (e.g., cardiac function, renal function) are preserved. Informed concent is obtained from the patient.
Exclusion criteria
Exclusion criteria: In status of myelosuppression. Serious infectious lesion exists in head or neck region. Serious complications exist(interstitial pneumonia, uncontrolable diabetes, heart failure, renal dysfunction, liver dysfunction, etc). Viable double cancer or other malignant disease exists. Patients who have past history of radiation therapy to head and neck region. Patients who have allergic history for iodine contrast medium or platinums. Patients who have serious mental disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| local control rate | — |
Secondary
| Measure | Time frame |
|---|---|
| primary tumor response rate, frequency and grade of adverse event, 5 years survival rate and reurrence rate | — |
Countries
Japan
Contacts
Public ContactNorimitsu Tanaka
Kurume University Department of Radiology
Outcome results
None listed