Effects of cold exposure on energy expenditure by brown adipose tissue in humans

Effects of cold exposure on energy expenditure by brown adipose tissue in humans - Brown adipose tissue and cold exposure

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009005

Enrollment

Registered

2012-10-01

Start date

2011-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy male volunteers

Interventions

Participants were exposed to cold at 15-17C for 2 hr every day. After 6 weeks, their brown adipose tissue activity, body fat content, and whole-body energy expenditure were measured at a resting state

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1. Healthy male volunteers 2. Aged 20-30 years 3. Be able to provide written informed consent

Exclusion criteria

Exclusion criteria: Body mass index >=30

Design outcomes

Primary

Measure	Time frame
Whole body energy expenditure assessed from respiratory gas analysis. Activity of brown adipose tissue assessed by FDG-PET/CT.	—

Secondary

Measure	Time frame
Body fat content	—

Countries

Japan

Contacts

Public ContactSaito, Masayuki

Tenshi College School of Nursing and Nutrition

saito@tenshi.ac.jp

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026