gynecological open surgery
Conditions
Interventions
control group was set as patients who received postoperative epidural infusion (2ml/hour) of 0.2% ropivacaine 100ml containing morphine 6 mg and butorphanol 2 mg with no epinephrine.
E0.15 group was s
Sponsors
Japanese Red Cross Society Wakayama Medical Center
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: ASA physical status 1-2
Exclusion criteria
Exclusion criteria: Patients were excluded from the study if one or more of the following criteria were met: allergy to opioids, concurrent use of antidepressants or analgesics, smoking habit, medical histories of chronic inflammatory disease and motion sickness, severe obesity (BMI > 25), contraindications to epidural catheterization such as infection, anatomical abnormalities of the spine, or full anticoagulation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint was the incidence of pruritus during the postoperative 24 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| The following measures were selected at the secondary endpoint: incidences of dizziness, incidences of postoperative emesis (none, nausea, retching, and vomiting), intensities of postoperative wound pain: Visual analogue scales (VAS, mm: 0 = no pain, 100 = worst pain imaginable, at rest and at coughing), and incidences of side effects. | — |
Countries
Japan
Outcome results
None listed