Effect of febuxostat on vascular endothelial function in patients with hyperuricemia

Effect of febuxostat on vascular endothelial function in patients with hyperuricemia - Effect of febuxostat on vascular endothelial function in patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008900

Enrollment

Registered

2012-09-11

Start date

2012-08-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hyperuricemia

Interventions

febuxostat (+ nutrition education) Control group (nutrition education)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Hyperuricemic patients who's uric acid level is over 7.0mg/dL

Exclusion criteria

Exclusion criteria: 1.Pregnant or nursing woman 2.Diabetic patients who's HbA1c(NGSP) is over 8.4% 3.Patients with having past history of allergic event 4.Patients with severe liver injury or severe renal insufficiency 5.Patients who's systolic blood pressure is over 160mmHg and/or diastolic blood pressure is over 110mmHg 6.Ineligible patients for any other reasons

Design outcomes

Primary

Measure	Time frame
flow-mediated vasodilation	—

Countries

Japan

Contacts

Public ContactTakuya Ohashi

Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University Department of Molecular Endocrinology and Metabolism

dept.mem@tmd.ac.jp03-5803-5216

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026