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The open label parallel intergroup trial about the influence on the tear fluid osmotic pressure by an instillation therapy to dry eye patients

The open label parallel intergroup trial about the influence on the tear fluid osmotic pressure by an instillation therapy to dry eye patients - Influence of the tear fluid osmotic pressure on dry eye's eye drops

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000008873
Enrollment
30
Registered
2012-09-18
Start date
2012-09-18
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dry eye

Interventions

sodium hyaluronate eye drop Rebamipide eye drop

Sponsors

Nippon Medical School Ophthalmology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: A patient aged 20 and over (sex unquestioned) The patient diagnosed as the example of dry eye decision, or the example of doubt based on dry eye diagnostic criteria (2006) Hospitalization or visitors; unquestioned The patient by whom consent is got in written form

Exclusion criteria

Exclusion criteria: The patient who has merged anterior ocular segment diseases except for dry eye The patient who is using the patient and the steroid, anti-inflammatory agent, and immunosuppressant The patient by whom change of eye drops (prescription medicine, OTC medicine) is expected from an inspection till the end of trial drug The patient for contact lens wearing The patient who has the eye operation history within 12 months The patient who enforced insertion of a punctal plug, or a surgical punctal closing way within one month The patient to whom the examination responsibility doctor or the examination assignment doctor judged the participation in this research to be unsuitable

Design outcomes

Primary

MeasureTime frame
tear fluid osmotic pressure inflammatory cytokine

Secondary

MeasureTime frame
fluorescein corneal staining score lissamine corneal staining score breaking up time

Countries

Japan

Contacts

Public ContactTomonaga Takase

Nippon Medical School IRB

clinicaltrial@nms.ac.jp03-3822-2131

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026