A clinical study of the usefulness of a neutrophil elastase inhibitor in patients with postoperative acute exacerbation of interstitial pneumonia complicated with lung cancer

A clinical study of the usefulness of a neutrophil elastase inhibitor in patients with postoperative acute exacerbation of interstitial pneumonia complicated with lung cancer - A clinical study of the usefulness of a neutrophil elastase inhibitor in patients with postoperative acute exacerbation of interstitial pneumonia complicated with lung cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008862

Enrollment

120

Registered

2012-09-10

Start date

2009-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Interstitial pneumonia combine with lung cancer

Interventions

Sivelestat sodium treatment group Non-sivelestat sodium treatment group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with image findings of interstitial pneumonia who are scheduled for surgery for primary lung cancer

Exclusion criteria

Exclusion criteria: 1) Patients with a history of sensitivity to sivelestat sodium 2) Patients judged inappropriate by attending physicians

Design outcomes

Primary

Measure	Time frame
Presence or absence of postoperative acute exacerbation	—

Secondary

Measure	Time frame
PaO2/FIO2,Laboratory values(KL-6,SP-A,SP-D,LDH,CRP)	—

Countries

Japan

Contacts

Public ContactKazuya Takamochi

Juntendo University School of Medicine General Thoracic Surgery

03-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026