Colorectal adenomas or early colorectal cancers to be resected by endoscopic submucosal dissection (ESD)
Conditions
Interventions
Covering ulcer bed made after colorectal ESD with Neoveil and Beriplast
Sponsors
NTT Medical Center Tokyo, Department of Gastroenterology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Adult patients who will undergo colorectal ESD at our hospital and have given written informed consent to this study.
Exclusion criteria
Exclusion criteria: 1. Those who fall under the category of contraindication of Neoveil or Beriplast. Neoveil: those who have systematic complications Beriplast: 1) those who have a history of anaphylaxis to components of Beriplast or drugs made of bovine lung, such as aprotinin 2) those who are treated with procoagulants (hemocoagulase made from snake venom), antifibrolytic agents, and aprotinin 2. Those who are considered to be inappropriate for this study by doctors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The extent of remaining Neoveil on the ulcer bed 8 to 14 days after ESD | — |
Secondary
| Measure | Time frame |
|---|---|
| procedure time / success rate of covering / complications associated with the procedure / body temperature, the number of white blood cell, the value of C-reactive protein, and the presence of abdominal pain the next day after colorectal ESD. | — |
Countries
Japan
Outcome results
None listed