Clinical study of combination of Helicobacter pylori eradication therapy and ingestion of bifidobacteria-fermented milk

Clinical study of combination of Helicobacter pylori eradication therapy and ingestion of bifidobacteria-fermented milk - Clinical study of combination of Helicobacter pylori eradication therapy and ingestion of bifidobacteria-fermented milk

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008834

Enrollment

200

Registered

2012-09-01

Start date

2012-07-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection

Interventions

Lactobacillus-fermented milk Placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)Subjects from 20 to 79 years old (2)H. pylori-positive subjects (3)H. pylori positive subjects who wants to be treated with H. pylori eradication therapy (4)Subjects who can be distinguished between CAM-susceptible and CAM-resistant H. pylori carrier

Exclusion criteria

Exclusion criteria: (1)Subjects who are allergic to lactobacillus-fermented milk (2)Subjects with drug allergy (3)Subjects treated with proton pump inhibitor therapy one month before the screening test (4)Subjects treated with H. pylori eradication therapy (5)Subjects with bronchial asthma (6)Subjects with severe liver disease, renal dysfunction, and heart disease (7)Subjects judged as unsuitable for this study based on the results of clinical examination (8)Subjects who participate in other clinical trials (9)Subjects who are pregnant or lactating, or intending to become pregnant during the study (10)Subjects judged as unsuitable by the doctor

Design outcomes

Primary

Measure	Time frame
Urea breath test H. pylori stool antigen H. pylori IgG antibody Pepsinogen I Pepsinogen II Pepsinogen I/II Gastrin intestinal flora Intestinal organic acids/metabolite GSRS FSSG ROME III FGID POMS short version	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026