Dose escalation trial to evaluate the safety and the efficacy on new bone formation of a single local treatment with lithium carbonate to teeth extraction sockets for dental implant in Japanese participants

Dose escalation trial to evaluate the safety and the efficacy on new bone formation of a single local treatment with lithium carbonate to teeth extraction sockets for dental implant in Japanese participants - Dose escalation trial to evaluate the safety and the efficacy on new bone formation of a single local treatment with lithium carbonate

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008795

Enrollment

Registered

2012-08-29

Start date

2012-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dental implant

Interventions

Local treatment with lithium carbonate

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Japanese (<20 years, < 70 years old) who will be extracted molar and placed implant at Implant Center in Kyushu University Hospital

Exclusion criteria

Exclusion criteria: 1 Person who is diagnosed as osteoporosis 2 Person who is suffered from bone disease 3 Person who is not allowed the treatment with lithium carbonate 4 Person who is treated with the medicine which may cause drug interaction with lithium carbonate 5 Body weight<40 kg, >90 kg 6 Person who has a periapical lesion in object tooth 7 Person who has 1- or 2-wall infrabony defects after object tooth extraction 8 Person judged as inappropriate by research contact person

Design outcomes

Primary

Measure	Time frame
Evaluation of the safety of the local treatment with lithium carbonate	—

Countries

Japan

Contacts

Public ContactFumi Takahashi

Facluty of Medical Sciences, Kyushu Univ Clinical Pharmacology

yanaga@clipharm.med.kyushu-u.ac.jp092-642-6082

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026