Evaluation of Nasal High Flow Oxygen Therapy for Severe Acute Hypoxemic Respiratory Failure.

Evaluation of Nasal High Flow Oxygen Therapy for Severe Acute Hypoxemic Respiratory Failure. - Evaluation of Nasal High Flow Oxygen Therapy.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008778

Enrollment

Registered

2012-08-27

Start date

2012-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe acute hypoxemic respiratory failure

Interventions

Nasal High Flow Oxygen Therapy Non Invasive Ventilation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.admitted to respiratory department of our hospital for severe acute hypoxemic respiratory failure(AHRF) other than cardiogenic pulmonary edema 2.met the standard clinical and/or blood gas criteria for use of NIV to treat severe AHRF 3.have received NIV for less than 12 hours

Exclusion criteria

Exclusion criteria: 1.hypercapnia (PaCO2>45mmHg) 2.unstable clinical conditions (i.e., need for vasopressors, metabolic acidosis, life-threatening arrhythmias, need for FiO2>=0.8, agitation and anxiety 3.inability to obtain consent 4.face or neck deformities 5.use of NIV before admission 6.need for continuous sedation

Design outcomes

Primary

Measure	Time frame
Interface discomfort	—

Secondary

Measure	Time frame
dyspnea easy to speak, sleep perception, easy to eat and drink arterial blood gas analysis vital signs early failure length of ICU stay length of hospital stay in-hospital mortality 90-day survival complications	—

Countries

Japan

Contacts

Public ContactKazuma Nagata

Kobe City Medical Center General Hospital Department of Respiratory Medicine

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026