Eye fatigue, dry eye
Conditions
Interventions
Dietary supplement containing bilberry extract
Placebo without containing bilberry extract
Sponsors
ShinYokohama shinoharaguchi orthopedic surgery/ dermatology, Medical Corporation Jico-kai Yagi Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Workers using visual display terminal 2) Subjects with subjective eye fatigue 3) Subjects with lowered critical flicker frequency and lowered near point distance
Exclusion criteria
Exclusion criteria: 1) Corrected visual acuity < 1.0 2) High myopia 3) Routine use of bilberry extract, -enriched food or medicines with visual function-improving activity 4) Ophthalmic disorder and/or a history of severe ophthalmic disorder 5) Strabismus 6) Previous visual dysfunction due to cataract (congenital, senile, diabetic, complicated or traumatic) or glaucoma (chronic, acute, congenital, secondary) 7) A risk for developing pollinosis between July and December 8) Under medical treatment, or a history serious disease needing medical treatment 9) Lasik operation undergone within 3 month 10) Allergy to study diet 11) Participation in other clinical trial within a month 12) Expecting a pregnancy or lactation during the study period 13) Judged as unsuitable for the study based on the results of questionnaire 14) Judged to be excluded from the study by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Critical flicker frequency, near point distance (amplitude of accommodation) | — |
Secondary
| Measure | Time frame |
|---|---|
| Contrast sensitivity, functional visual acuity, BUT, keratconjunctival disorder, amount of lacrimal fluid storage (strip meniscometry), questionnaire | — |
Countries
Japan
Outcome results
None listed