elderly patients with stage IIIB/IV non-small cell lung cancer except for squamous cell carcinoma
Conditions
Interventions
Sponsors
Department of Respiratory Medicine and Rheumatology, Institute of Health Biosciences, The University of Tokushima Graduate School
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) histologically confirmed non-small cell lung cancer except for squamous cell carcinoma 2) clinical stage IIIB/IV or relapsed case 3) chemotherapy naive 4) PS (ECOG) 0-1 5) with mesurable lesions 6) more than 75 years old 7) with sufficient bone marrow, liver and kidney function 8) with asymptomatic and/or well controled brain metastases 9) estimated survival is more than 3 months 10) with written informed consent
Exclusion criteria
Exclusion criteria: 1) history of hemoptysis (more than 2.5mL) 2) with pulmonary cavitary lesions 3) with invasion to the aorta and/or pulmonary arteries 4) tumor outcrop in main bronchus 5) history of radical thoracic radiotherapy 6) patients treated by anti-coagulation therapy complicated with brain metastasis 7) with severe infection 8) with massive pleural effusion, ascites or pericardial effusion 9) overlapped with other malignancies 10) with severe peptic ulcer 11) history of perforation in digestive tract
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| response rate | — |
Secondary
| Measure | Time frame |
|---|---|
| disease control rate, progression free survival, overall survival, safety, QOL | — |
Countries
Japan
Contacts
Public ContactMasaki Hanibuchi
The University of Tokushima Graduate School, Institute of Health Biosciences Department of Respiratory Medicine and Rheumatology
Outcome results
None listed