Infertile patient and poor responder in controlled ovarian hyperstimulation
Conditions
Interventions
hMG-GnRH antagonist: start HMG(FSH:LH 1:1) from day3 until the day of hCG administration. Concomitant treatment with Ganirelix 0.25mg s.c. in multiple, flexible method when leading follicle reaches 14
Sponsors
Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) require IVF-ET for infertility treatment 2) less than four-times-history of controlled ovarian hyper stimulation with GnRH antagonist 3) Exhibit ovarian dysfunction by the findings such as basal FSH above 10 mIU/ml, antral follicle count below 7, and oocyte retrieval below 5 in the previous cycle.
Exclusion criteria
Exclusion criteria: 1) above 46 years of age 2) not allowed to be pregnant due to other medical complications 3) scheduled to undergo freezing of all embryos due to gynecological conditions such as myomas and adenomyosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate the clinical pregnancy rate per ovarian stimulation, oocyte retrieval, and embryo transfer. | — |
Countries
Japan
Contacts
Public ContactHajime Oishi
The University of Tokyo, Faculty of Medicine Department of Obstetrics and Gynecology
Outcome results
None listed