Effect of ropivacaine concentration on the distribution of neural blockade in continuous thoracic paravertebral block

Effect of ropivacaine concentration on the distribution of neural blockade in continuous thoracic paravertebral block - Effect of ropivacaine concentration on the distribution of neural blockade in continuous thoracic paravertebral block

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008729

Enrollment

Registered

2012-08-20

Start date

2011-10-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients scheduled for elective unilateral thoracotomy (lung lobectomy or pulmonary segmentectomy) under general anesthesia and continuous thoracic paravertebral block

Interventions

Postoperative continuous thoracic paravertebral block of ropivacaine 0.2% 6mL/h for 48 hours Postoperative continuous thoracic paravertebral block of ropivacaine 0.5% 6mL/h for 48 hours

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Patients undergoing unilateral lung lobectomy or pulmonary segmentectomy at Niigata University Medical and Dental Hospital 2.American Society of Anesthesiologists Physical Status Classification I-III 3.Written informed consent is provided

Exclusion criteria

Exclusion criteria: 1. Inability to communicate lucidly 2. Under 20 years old or over 80 years old 3. Bilateral thoracotomy 4. Patient with a past history of thoracotomy on the same side as the surgery 5. Allergy to local anesthetics 6. Contraindication to NSAIDs or fentanyl 7. ASA-PS > III 8. Hemodialysis patients 9. Body Mass Index > 30 kg/m^2 10. Body weight < 40 kg 11. Chronic opioid use 12. Neurological disability 13. Infections at the site of injection

Design outcomes

Primary

Measure	Time frame
Number of anesthetized dermatomes 24 hours after surgery	—

Secondary

Measure	Time frame
1.Pain score (Numerical Rating Scale) assessed at 1 hour, 6, 24, and 48 hours after surgery 2.The consumption of additional analgesics 3.Patient satisfaction score 4.Sedation score (Richmond Agitation Sedation Scale) 5.Incidence of nausea and vomiting	—

Countries

Japan

Contacts

Public ContactTakayuki Yoshida

Niigata University Medical and Dental Hospital Department of Anesthesiology

ytaka@med.niigata-u.ac.jp025-227-2328

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026