Pharmacokinetic study of fine granules of Kracie shoseiryuto extract in human blood

Pharmacokinetic study of fine granules of Kracie shoseiryuto extract in human blood - Pharmacokinetic study of fine granules of Kracie shoseiryuto extract

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008722

Enrollment

Registered

2012-08-20

Start date

2011-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

none

Interventions

Administration of 6.0g fine granules of Kracie kakkonto extract with 270ml of water and 270mL of Kakkonto standard decoction 2 weeks afterward. Administration of 270 mL of Kakkonto standard decoction

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Healthy male volunteers between 20 and 65 years of age who give informed consent.

Exclusion criteria

Exclusion criteria: 1.Those who donated blood during the past four months 2. Those who have a history of angina pectoris 3. Those who are suffering from dysuria 4. Those who are suffering from serious hepatic disorder, renal disease, heart disorder, pneumopathy or blood dyscrasias 5. Those who are taking supplements or vitamins on a regular basis. 6. Those who are judged by a medical doctor not eligible for the examination.

Design outcomes

Primary

Measure	Time frame
Pharmacokinetic parameters of glycyrrhizic acid, Ephedrine, Pseudoephedrine, Paeoniflorin and their metabolites, and safety assessment of the fine granules	—

Countries

Japan

Contacts

Public ContactKei Hamazaki

Polyene Project , Ltd Dept of Clinical Science

076-434-7617

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026