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The influence of oral valproate on propofol metabolism

The influence of oral valproate on propofol metabolism - The influence of oral valproate on propofol metabolism

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000008711
Enrollment
48
Registered
2012-08-18
Start date
2012-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with oral valproate

Interventions

None listed

Sponsors

Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Department of Dental Anesthsiology and Special Care Dentistry
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Participants of the present study are patients who have the plan of a general anesthesia in Okayama university hospital.

Exclusion criteria

Exclusion criteria: Patients without consent of the study

Design outcomes

Primary

MeasureTime frame
The change of BIS index during anesthesia induction, the serum concentration of propofol after injection and the change of blood pressure and heart rate during anesthesia

Countries

Japan

Contacts

Public ContactHitoshi Higuchi

Okayama University Hospital Dental Anesthesiology

higuti@md.okayama-u.ac.jp086-235-6721

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026