Efficacy of automated carbon dioxide insufflation and IV Buscopan as a muscle relaxant in computed tomography colonography.

Efficacy of automated carbon dioxide insufflation and IV Buscopan as a muscle relaxant in computed tomography colonography. - Efficacy of automated CO2 insufflation and IV Buscopan in CT colonography

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008690

Enrollment

200

Registered

2012-08-15

Start date

2012-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy individual

Interventions

Automated carbon dioxide insufflation with intravenous injection of butyl scopolamine (Buscopan) Manual carbon dioxide insufflation without butyl scopolamine (Buscopan) Manual carbon dioxide insuffla

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Healthy individual. 2) Major functions of organs of the subjects are in a good condition. 3) Aged 40 years or older. 4) Signed informed consent forms are obtained by the patients.

Exclusion criteria

Exclusion criteria: 1) Patients with inflammatory bowel disease. 2) Fulfillment of clinical criteria for diagnosis of FAP or HNPCC (Amsterdam criteria). 3) Contraindication for using Buscopan. 4) Previous colorectal surgery. 5) Gastric or intestinal stenosis, abdominal adhesions, bowel obstruction or perforation, toxic megacolon. 6) Evidence of an increased risk in carrying out bowel preparation or CTC exams. 7) Possibility of pregnancy. 8) Patients with psychological conditions that contraindicate colonoscopy or make them irrelevant to participate in the trial. 9) Claustrophobia. 10) Severe deafness. 11) Subjects whose eligibility for this clinical trial is not appropriate by other reasons.

Design outcomes

Primary

Measure	Time frame
Assessment of colon and small intestine distension per segment using a 4-point scale (prone and supine).	—

Secondary

Measure	Time frame
Data on perceived burden of CT colonography were collected using visual analogue scale (VAS) and a questionnaire.	—

Countries

Japan

Contacts

Public ContactKoichi Nagata M.D PhD

Kameda Medical Center Makuhari Department of Gastroenterology

Nagata7@aol.com043-296-2711

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026