food allergy
Conditions
Interventions
Subjects are fed with 50 mg of egg powder daily starting at six months old. After three months, amount of egg powder is increased to 250mg. During the intervention, subjects are not allowed to eat any
Sponsors
National Center for Child Health and Development
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Infants aged four to five months old who were diagnosed with atopic dermatitis by a physician.
Exclusion criteria
Exclusion criteria: (1) Infants born before 37 weeks of gestation. (2) Infants who have already being fed with egg. (3) Infants with a history of immediate type allergic reaction to egg. (4) Infants with possible atypical food allergy other than immediate type food allergy. (5) Infants with severe complications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Negative diagnostic rate of food challenge test with hen's egg at one year old. | — |
Secondary
| Measure | Time frame |
|---|---|
| Measurement of the following bio markers of the subjects at their entry, nine months old and one year old: - antigen-specific antibody IgG1, IgG4, IgA and IgE in serum. - serum TARC. - antigen-specific antibody IgG1, IgG4, IgA and IgE in saliva. | — |
Countries
Japan
Contacts
Public ContactShigenori Kabashima, Osamu Natsume
National Center for Child Health and Development Division of allergy
Outcome results
None listed