Prospective study of the efficacy of pancreatic enzyme replacement therapy for non-alcoholic fatty liver disease after pancreatectomy

Prospective study of the efficacy of pancreatic enzyme replacement therapy for non-alcoholic fatty liver disease after pancreatectomy - Prospective study of the efficacy of pancreatic enzyme replacement therapy for non-alcoholic fatty liver disease after pancreatectomy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008556

Enrollment

Registered

2012-07-30

Start date

2012-07-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic or biliary tract disease required pancreatectomy

Interventions

Pancreatic enzyme replacement therapy after pancreatectomy Control group (no treatment)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with pancreatic or biliary tract disease requiring pancreatectomy

Exclusion criteria

Exclusion criteria: 1.Patients with acute ischemic heart disease 2.Patients with preoperative fatty liver/liver cirrhosis, viral hepatitis or alcoholic liver disease 3.Patients with heavy use of alcohol 4.Patients with interstitial pneumonia or fibroid lung who require oxygen administration 5.Patients with chronic renal failure requiring dialysis 6.Patients with other malignant disease 7.Patients who have a hypersensitivity to Lipacreon&#174; or pig protein 8.Patients who are diagnosed to be ineligible by the investigator

Design outcomes

Primary

Measure	Time frame
The incidence of non-alcoholic fatty liver disease three months after surgery	—

Secondary

Measure	Time frame
The incidence of exocrine pancreatic insufficiency three months after surgery	—

Countries

Japan

Contacts

Public ContactKenichiro Uemura

Hiroshima University Hospital Gastrointestinal Surgery

082-257-5216

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026