GERD
Conditions
Interventions
no additional treatment
Additional treatment of esomeprazole for 6 weeks
Sponsors
Tokai University School of Medicine
Showa University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: LA grade A or B diagnosed by esophagoscopy within 6 months Having GER symptoms Disappearance of GER symptoms after the treatment by esomeprazole (20 mg/day for 2 weeks) by GerdQ questionnaire
Exclusion criteria
Exclusion criteria: Patiets with the history of gastric surgeries Patients with alarm symptoms such as vomiting, GI bleeding, rapid body weight loss Patients of alcohol or drug dependence Patients with severe endocrine problems Patients with severe injuries of heart, liver, kidney or bone marrow functions Patients with allergy against the test drugs Patients with pregnancy, possible pregnancy or breast feeding, or hope of pregnancy during the test period Patients whom the doctor decide as not proper for the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| length of the GER symptom free periods after the treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) factors affecting the relapse of GERD 2) difference of GER symptoms between before and after the 2 week treatment and the rates of the disappearance of GER symptoms 3) the severity of GER symptoms in case of the relapse | — |
Countries
Japan
Contacts
Public ContactMasashi Matsushima
Tokai University Tokyo Hospital Internal Medicine (Gastroenterology)
Outcome results
None listed