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Evaluation of the correlation between low-dose aspirin-induced small bowel injuries and serum thromboxane B2 levels

Evaluation of the correlation between low-dose aspirin-induced small bowel injuries and serum thromboxane B2 levels - Correlation between LDA-induced small bowel injuries and serum TXB2 levels

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000008515
Enrollment
100
Registered
2012-07-25
Start date
2012-07-24
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

small bowel mucosal injury

Interventions

None listed

Sponsors

Division of Endoscopy, Yokohama City University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with chronic LDA use (more than three months) prior this study 2. Willingness to provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. History of NSAIDs use within three months prior this study 2. History of inflammatory bowel disease 3. History of severe renal failure and/or hepatic failure 4. Patients with implantable pacemaker 5. Patients with dysphagia. 6. Patients who have history of the ileus or stricture or fistula of the intestine. 7. Patients who can not give informed consent for operation to retrieve the capsule. 8. The patients who have severe heart failure and respiratory failure. 9. Patients judged as inappropriate candidates for the trial by the investigators

Design outcomes

Primary

MeasureTime frame
Capsule endoscopic findings and the serum TXB2 levels in low-dose aspirin users

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026