Evaluation of the correlation between low-dose aspirin-induced small bowel mucosal injury and cardiovascular/cerebrovascular events: multicenter prospective cohort study

Evaluation of the correlation between low-dose aspirin-induced small bowel mucosal injury and cardiovascular/cerebrovascular events: multicenter prospective cohort study - Evaluation of the correlation between LDA-induced small bowel mucosal injury and cardiovascular/cerebrovascular events

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000008510

Enrollment

300

Registered

2012-07-25

Start date

2012-07-24

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

small bowel mucosal injury and cardiovascular/cerebrovascular disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who take low-dose aspirin more than three months prior this study for prevention for cardiovascular events (AP and AMI) and cerebrovascular (CI and TIA). 2. Willingness to provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. History of NSAIDs use within three months prior this study 2. History of inflammatory bowel disease 3. History of severe renal failure and/or hepatic failure 4. Patients with implantable pacemaker 5. Ppatients with dysphagia. 6. Patients who have history of the ileus or stricture or fistula of the intestine. 7. Patients who can not give informed consent for operation to retrieve the capsule. 8. The patients who have severe heart failure and respiratory failure. 9. Patients judged as inappropriate candidates for the trial by the investigators

Design outcomes

Primary

Measure	Time frame
The incidence rate of cardiovascular/cerebrovascular events	—

Countries

Japan

Outcome results