Witnessed cardiac arrest(except cardiac arrest due to trauma)
Conditions
Interventions
Patients in the treatment group will undergo 2 hours of pharyngeal cooling during resuscitation or early after recovery of spontaneous circulation.
Patients in the control group will undergo standar
Sponsors
Okayama University Medical School
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with witnessed cardiogenic cardiac arrest or witnessed non-cardiogenic cardiac arrest except posttraumatic cardiac arrest. 2. Patients who have been resuscitated by medical services within 15 min after the onset of cardiac arrest.
Exclusion criteria
Exclusion criteria: 1. Patients with a disorder in the pharynx or esophagus. 2. Patients with severe hypothermia (less than 34 degrees centigrade upon arrival). 3. Patients who are pregnant. 4. Patients with an immunodeficiency or medicated with an immunosuppressant. 5. Patients with brain damage initiated by a mechanism other than cardiac arrest. 6. Rejection by a person in parental authority. 7. Score of Barthel index of less than 66.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality rates at 1 month, 3 months and 6 months after resuscitation | — |
Secondary
| Measure | Time frame |
|---|---|
| Time until tympanic temperature reaches 32.0 degrees centigrade after arrival at the hospital. Glasgow Coma Scale at 2 weeks after resuscitation Glasgow Pittsburgh cerebral performance and overall performance categories at 1 month and 6 months after resuscitation | — |
Countries
Japan
Contacts
Public ContactYoshimasa Takeda, MD, PhD
Okayama University Medical School Anesthesiology
Outcome results
None listed