Evaluation of the effect of Propolis on insulin resistance in patients with type 2 diabetes.

Evaluation of the effect of Propolis on insulin resistance in patients with type 2 diabetes. - Evaluation of the effect of Propolis on insulin resistance in patients with type 2 diabetes.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008479

Enrollment

100

Registered

2012-07-20

Start date

2012-07-23

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes

Interventions

Brazilian Green Propolis (226.8mg/day) placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with written informed consent. 2) Aged over 30 years and under 80 years. 4) Type of practice: outpatient department. 5) Patients who will keep the rules to intake and to visit hospital.

Exclusion criteria

Exclusion criteria: 1) Patients who did not agree with joining this study. 2)Patients with severe renal dysfunction or severe hepatic dysfunction. 3)Pregnant women, women who may be pregnant, and breast-feeding women. 4)Patients treated with insulin. 5)Patients who are ineligible for some other reason judged by attending physician.

Design outcomes

Primary

Measure	Time frame
Change in HOMA-IR after 8 weeks of treatment	—

Secondary

Measure	Time frame
Changes in FPG,HbA1c,total cholesterol, HDL,LDL,triglyceride,serum insulin,remnant like particle cholesterol(RLP-C),HMW-adiponectin,TNF-alpha,high sensitive CRP,IL-6 and urine pH after 8 weeks of treatment.	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026