Patients with preoperative EFs 40% or less who undergo cardiovascular operations using cariopulmonary bypass machine or Off Pump CABG (OPCAB) in the Department of Cardiovascular Surgery, Osaka University Hospital.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients without preoperative chronic atrial fibrillation.
Exclusion criteria
Exclusion criteria: 1. Patients with cardiogenic shock 2. Patients with diabetic ketoacidosis and metabolic acidosis 3. Patients with bradycardia such as atrioventricular block (II degree or higher) and sick sinus syndrome 4. Patients with right heart failure due to pulmonary hypertension 5. Patients with congestive heart failure 6. Patients with untreated pheochromocytoma 7. Patients with a past history of hypersensitivity to landiolol 8. Patients with congenital heart diseases 9. Patients undergoing heart transplantation 10. Patients with ventricular assisted devices 11. Patients with ECMO 12. Patients having atrial fibrillation immediately before administration of landiolol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| occurrence of postopeartive atrial fibrillation | — |
Countries
Japan