Association of HLA-DR gene polymorphism and systemic lupus erythematosus (SLE) associated genes (IRF5, BLK, STAT4, TNFAIP3, TNIP1, ETS1 and SPP1 polymorphisms) with childhood-onset SLE.

Association of HLA-DR gene polymorphism and systemic lupus erythematosus (SLE) associated genes (IRF5, BLK, STAT4, TNFAIP3, TNIP1, ETS1 and SPP1 polymorphisms) with childhood-onset SLE. - Association of HLA-DR gene polymorphism and systemic lupus erythematosus (SLE) associated genes (IRF5, BLK, STAT4, TNFAIP3, TNIP1, ETS1 and SPP1 polymorphisms) with childhood-onset SLE.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000008459

Enrollment

300

Registered

2012-07-20

Start date

2010-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

systemic lupus erythematosus

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients with childhood-onset SLE treated in our hospital and with obtained prior written informed consent from patients and/or their parents.

Exclusion criteria

Exclusion criteria: The patient judged as improper case for enrollment in this study.

Design outcomes

Primary

Measure	Time frame
Prevalence of SLE	—

Secondary

Measure	Time frame
Subgroup analysis based on (1)clinical characteristics, (2)response to therapy, (3)the level of anti-dsDNA peptide antibodies, antinuclear antibody or complement, (4)family history of rheumatic disease and autoimmune disease, (5)complications such as renal failure.	—

Countries

Japan

Contacts

Public ContactShumpei Yokota

Yokohama City University Graduate School of Medicine Department of Pediatrics

kxqxk574@yahoo.co.jp045-787-2671

Outcome results