Peripheral leukocyte function as a predictive marker of endoscopic activity and efficacy of apheresis in patients with ulcerative colitis

Peripheral leukocyte function as a predictive marker of endoscopic activity and efficacy of apheresis in patients with ulcerative colitis - Peripheral leukocyte function in patients with ulcerative colitis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000008448

Enrollment

Registered

2012-08-01

Start date

2012-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative colitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The relationship between peripheral leukocyte function and endoscopic activity: Remission stage (n=20), Active stage (n=20) 2. The relationship between peripheral leukocyte function and effect of granulocyte and monocyte adsorptive apheresis: Active stage (>=CAI 7) patients who were treated with granulocyte and monocyte adsorptive apheresis (n=30) or tacrolimus (n=10)

Exclusion criteria

Exclusion criteria: Patients with known renal dysfunction, severe hepatic dysfunction or malignancy, and pregnant women were excluded, ect.

Design outcomes

Primary

Measure	Time frame
The relationship between peripheral leukocyte function and efficacy of granulocyte and monocyte adsorptive apheresi	—

Secondary

Measure	Time frame
The relationship between peripheral leukocyte function and endoscopic activity	—

Countries

Japan

Contacts

Public ContactToshihiro Inokuchi

Okayama University Hospital Department of Gastroenterology

sakikoh@cc.okayama-u.ac.jp086-235-7219

Outcome results