Asthma
Conditions
Interventions
The group which changed LTRA into IPD without the increasing the quantity of ICS . (A group) Before randomization ,The group is continuing the combined therapy of LTRA and ICS for four weeks or more
the apparent severity of illness"
of JPGL 2008 of the group is more than mild persistent asthma and the control state of the group is bad by a JPAC questionnaire .
The group which increased the quantity of ICS 1.5 to 2.0 times (grou
of JPGL 2008 of the group is more than mild persistent asthma and the control state of the group is bad by a JPAC questionnaire .
Sponsors
Study group of the treatment of childfood asthma
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Case in which ICS and LTRA combined therapy were persisting four weeks or more. 2. "The apparent severity of illness" of JPGL 2008 is more than mild persistent asthma. 3.Case which receive Step 2 or Step 3 therapy based on JPGL2008. 4. Case as which control was poor and increase in quantity of medicine was considered as a result of judgment using JPAC questionnaire. 5.The case with which the selection criterion No2 and No3 are filled even if it sets the observation period for 4 weeks. 6. The age at the time of temporary registration is more than 2 years old and less than 15 years old
Exclusion criteria
Exclusion criteria: 1. Case which has anamnesis of hypersensitivity to spulatast tosilate. 2. Case which is using Symbicoat or Adair . 3. Case which newly uses systemic steroid from temporary registration date. 4. Case which receive newly hyposensitization or nonspecific immnotherapy from temporary registration date. 5. Case which has impaired liver function. 6. Case considered that there are complications, such as chronic bronchitis, pulmonary emphysema, and bronchiectasis, and it interferes with judgement of effect of a medicine . 7. In addition, case which has serious illness complications. 8. In addition, case which family doctor judged to be unsuitable as experimental object.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of chang of the asthma symptom score at the time of registration and the score at twelve week later.(The score made by the comittee of asthma severity judging standard of Japanese society of Allergology. | — |
Countries
Japan
Outcome results
None listed