Sarcopenia
Conditions
Interventions
Exercise + Placebo
Exercise + Nutritional supplementation 1
Exercise + Nutritional supplementation 2
Sponsors
Nestec Ltd
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: -Subject with gait speed between 0.6 and 1.2m/s -Age: 65-90years (inclusive) -Having obtained his/her (or his/her legal representative's) informed consent.
Exclusion criteria
Exclusion criteria: -Subject submitted to regular exercise -Obese subjects with BMI> 25kg/m2 -A history of neuromuscular problems. -Subject who cannot be expected to comply with the study procedures for the whole duration of the study -Currently participating or having participated in another clinical trial during the last 4 weeks prior to the beginning of this study. -Subject who currently takes or will take during the study other dietary supplements. -Subject who was diagnosed severe disease such as chronic renal failure, liver cirrhosis, heart failure, active cancer and other major systemic diseases or any health impairment considered as clinically significant by the investigator before admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be the change of the muscle size between week 12 and baseline in group 2 as compared to the same difference observed in group 1, measured by ultrasonography (muscle thickness and estimated muscle volume) | — |
Secondary
| Measure | Time frame |
|---|---|
| Muscle thickness and estimated muscle volume. body composition, gait speed, blood test between week 12 and baseline among three groups. | — |
Countries
Japan
Contacts
Public ContactProfessor Toshio Moritani
Kyoto University The Graduate School of Human & Environmental Studies
Outcome results
None listed