A clinical study of cancer peptides vaccine therapy in the patients who have recieved surgical resection and had no residual tumor for head and neck cancer

A clinical study of cancer peptides vaccine therapy in the patients who have recieved surgical resection and had no residual tumor for head and neck cancer - A clinical study of adjuvant peptides vaccine therapy after surgical resection of head and neck cancer

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000008380

Enrollment

Registered

2012-07-08

Start date

2010-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

head and neck cancer

Interventions

peptides vaccine therapy using URLC10, CDCA1, and KOC1-targeted peptides in the patients who have recieved surgical resection and had no tumor of head and neck cancer no peptides vaccine therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients who have no treatment against oral cancer. 2. Performance status of patients are 0-2. 3. more than 20, less than 85 years of age. 4. At least 4 weeks past after the patient has received last treatment. 5. Has adequate organ function as difined by following criteria. 1) WBC count more than 2000/mm3, less than 25000/mm3 2) Plt count more than 50000/mm3 3) AST and ALT less than 150IU/L 4) T.Bil less than 3.0mg/dl 5) Cr less than 3.0mg/dl 6) Patients who have HLA-A*2402. 7) All patients gave written informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnancy or lactation. 2. Patients who are treated with steroid or immunotherapy during clinical trial. 3. Patients have uncontrollable associated cancer. 4. Patients who are not agree. 5. Patients who are inappropriate.

Design outcomes

Primary

Measure	Time frame
safty	—

Secondary

Measure	Time frame
immunological response and clinical efficacy	—

Countries

Japan

Contacts

Public ContactYoshihiro Yoshitake

Graduated school of medicine Kumamoto University Department of Oral and Maxillofacial surgery

096-373-5288

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026