the hypertensive patient who has taken ARB and CCB
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: a) the hypertensive patient who has taken azelnidipine 16mg/day and olmesartan 20mg/day, or amlodipine 5mg/day and olmesartan 20mg/day, respectively, more than one month (4 weeks). b)the patient whose blood pressure at a mediacl office is below 159/99mmHg. c)the patinet above 20 years-old.
Exclusion criteria
Exclusion criteria: a) patient with previous allergic reaction to azelnidipine or olmesartan. b) female patient who has possibility of pregnancy. c) patient treated with azole antifungal drug or HIV protease inhibitor. d) patient who has taken hemodialysis or has severe renal dysfunction (serume creatine level is above 2.0mg/dL). e) patient considered to be improper to this study by attending doctor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change of systolic blood pressure at a medical office | — |
Secondary
| Measure | Time frame |
|---|---|
| change of diastololic blood pressure at a medical office, blood presssure at home, compliance of drug | — |
Countries
Japan
Contacts
Okayama Univesity Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Cardiovascular Medicine